SCHEMBL770276

SCHEMBL770276

CC(CO)C(CO)(CO)CCCCCCCCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.43
LMNA P02545 2/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43
GPR84 Q9NQS5 8/20 0.42
FFAR1 O14842 2/20 0.42
FFAR4 Q5NUL3 2/20 0.42
PPARG P37231 7/20 0.41
PPARD Q03181 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769558 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22GPR84
SCHEMBL5968433 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22GPR84
SCHEMBL6245028 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4948547 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22GPR84
SCHEMBL2702215 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22GPR84
SCHEMBL10597898 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22GPR84
SCHEMBL11739314 1.00 TSHR (0.43) TSHRLMNANFKB1PMP22GPR84
SCHEMBL4946734 0.98 LMNA (0.41) TSHRLMNANFKB1PMP22GPR84
Heptanoate SCHEMBL4946914 0.94 GPR84 (0.53) TSHRLMNAGPR84FFAR1FFAR4
Octanoic Acid SCHEMBL4945323 0.94 GPR84 (0.53) TSHRLMNAGPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0151859-B1 GREASE COMPOSITION MOBIL OIL CORPORATION (US) 1992-06-24 EP claimed
US-20210407702-A1 SURFACE PROTECTION COMPOSITION AND TERMINAL FITTED ELECTRIC WIRE AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2021-12-30 US disclosed
EP-1533361-B1 TIMEPIECE CONTAINING A GREASE COMPOSITION CITIZEN WATCH CO LTD (JP) 2018-06-27 EP disclosed
EP-1111028-B1 Engine oil composition NIPPON MITSUBISHI OIL CORP (JP) 2017-11-22 EP disclosed
CN-104204170-B Lubricant oil composite 吉坤日矿日石能源株式会社 2016-06-29 CN disclosed
CN-104220572-B Lubricant oil composite 吉坤日矿日石能源株式会社 2016-06-15 CN disclosed
CN-105452427-A Lubricant oil composition for internal combustion engine JX NIPPON OIL & ENERGY CORP 2016-03-30 CN disclosed
CN-104160002-B Variable-speed motor lubricating oil composition JX NIPPON OIL & ENERGY CORP. (JP) 2016-03-30 CN disclosed
US-20150376538-A1 FRICTION MODIFIER AND LUBRICATING OIL COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-12-31 US disclosed
CN-105102597-A Fuel-efficient engine oil composition JX NIPPON OIL & ENERGY CORP 2015-11-25 CN disclosed
EP-1111028-A9 Engine oil composition Nippon Mitsubishi Oil Corporation (JP) 2001-12-19 EP disclosed
US-20010027169-A1 Engine oil composition NIPPON MITSUBISHI OIL CORPORATION 2001-10-04 US disclosed
EP-0902828-B1 LUBRICATING GREASE COMPOSITIONS KLUEBER LUBRICATION (DE) 2001-08-22 EP disclosed
EP-1111028-A1 Engine oil composition Nippon Mitsubishi Oil Corporation (JP) 2001-06-27 EP disclosed
EP-0902828-A1 LUBRICATING GREASE COMPOSITIONS KLÜBER LUBRICATION MÜNCHEN KG (DE) 1999-03-24 EP disclosed
WO-1997047710-A1 LUBRICATING GREASE COMPOSITIONS KLüBER LUBRICATION MüNCHEN KG (DE) 1997-12-18 WO disclosed
US-5543081-A AN OIL DISPERSANT IS A REACTION PRODUCT OF AN AMINOAMIDE COMPOUND WITH BORIC ACID; HEAT RESISTANCE, HIGH TEMPERATURE CLEANINESS NIPPON OIL CO., LTD. (JP) 1996-08-06 US disclosed
US-5372703-A Dewaxing and dearomatizing a hydrocracked vacuum gas oil NIPPON OIL CO., LTD. (JP) 1994-12-13 US disclosed
EP-0435670-B1 Lubricating oils NIPPON OIL CO LTD (JP) 1994-08-24 EP disclosed
EP-0435670-A1 Lubricating oils NIPPON OIL CO. LTD. (JP) 1991-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376538-A1 FRICTION MODIFIER AND LUBRICATING OIL COMPOSITION SUGT1, SUMO1, SULT1A1 TSHR 4396/4885LMNA 3611/4885NFKB1 2723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.