Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.44 |
| ▸ | ITGAV | P06756 | 18/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644035 | 1.00 | ITGB3 (0.44) | ITGB3ITGAVITGA2BITGB5MAPT | |
| SCHEMBL4640251 | 0.92 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4641013 | 0.90 | ITGB3 (0.34) | ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL6882095 | 0.88 | STS (0.41) | ITGB3ITGAVITGA2BMAPT | |
| Benzene SCHEMBL6882109 | 0.87 | MAPT (0.35) | ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL6810562 | 0.87 | ITGB3 (0.41) | ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL6805791 | 0.86 | ITGB3 (0.44) | ITGB3ITGAVITGA2BMAPT | |
| SCHEMBL27524220 | 0.86 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4640164 | 0.86 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6876023 | 0.85 | SIRT2 (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196416-A1 | SUBSTITUTED PURINE DERIVATIVES AS INHIBITORS OF CELL ADHESION | Aventis Pharma Deutschland GmbH (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002399-A1 | SUBSTITUTED PURINE DERIVATIVES AS INHIBITORS OF CELL ADHESION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-11 | — | — | WO | disclosed |