Methacrylic Acid

Methacrylic Acid

SCHEMBL7703018

C1CCC2OC2C1.C=C(C)C(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
TFPI2 P48307 4/20 0.39
GMNN O75496 2/20 0.39
PMP22 Q01453 2/20 0.39
TP53 P04637 2/20 0.39
NFKB1 P19838 2/20 0.39
THPO P40225 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 2/20 0.35
CYP2C19 P33261 1/20 0.35
STAT6 P42226 1/20 0.35
HIF1A Q16665 1/20 0.35
NPC1 O15118 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
BLM P54132 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PPM1B O75688 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL2914629 0.80 TFPI2 (0.50) LMNATFPI2GMNNPMP22TP53
Bicarbonate SCHEMBL10352400 0.80 TFPI2 (0.50) LMNATFPI2GMNNPMP22TP53
SCHEMBL3685691 0.79 ALDH1A1 (0.58) LMNATFPI2GMNNPMP22TP53
SCHEMBL8643578 0.79 PPM1B (0.35) LMNATFPI2GMNNPMP22TP53
Acetamide SCHEMBL11056905 0.78 LMNA (0.42) LMNATFPI2GMNNPMP22TP53
Methacrylic Acid SCHEMBL4126214 0.78 ALDH1A1 (0.42) LMNATSHRTDP1ALDH1A1
Methacrylic Acid SCHEMBL479244 0.78 ALDH1A1 (0.42) LMNATSHRTDP1ALDH1A1
Methacrylic Acid SCHEMBL15441232 0.78 TFPI2 (0.38) LMNATFPI2GMNNPMP22TP53
Methacrylic Acid SCHEMBL4133803 0.76 ALDH1A1 (0.40) KDM4ENPC1RAB9ASMN1; SMN2TDP1
Methacrylic Acid SCHEMBL6065970 0.76 ALDH1A1 (0.40) KDM4ENPC1RAB9ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295001-A1 FUNCTIONALIZED EXFOLIATED NANOCLAY KANEKA AMERICAS HOLDING INC (US) 2023-09-21 US disclosed
CN-115836100-A Polymerizable composition, cured product, and method for producing cured product 株式会社艾迪科 2023-03-21 CN disclosed
CN-108541262-B Composition for window film, flexible window film, and flexible display device 三星SDI株式会社 2021-05-04 CN disclosed
US-20200172408-A1 FUNCTIONALIZED EXFOLIATED NANOCLAY KANEKA AMERICAS HOLDING INC (US) 2020-06-04 US disclosed
US-10023760-B2 Semicarbazide composition, method for producing semicarbazide composition, aqueous polymer composition and composite ASAHI KASEI CHEMICALS CORPORATION (JP) 2018-07-17 US disclosed
US-9919301-B2 Photocatalyst-supporting structure NIPPON SODA CO., LTD. (JP) 2018-03-20 US disclosed
US-20150291831-A1 SEMICARBAZIDE COMPOSITION, METHOD FOR PRODUCING SEMICARBAZIDE COMPOSITION, AQUEOUS POLYMER COMPOSITION AND COMPOSITE ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-10-15 US disclosed
US-20140323290-A1 PHOTOCATALYST-SUPPORTING STRUCTURE NIPPON SODA CO., LTD. (JP) 2014-10-30 US disclosed
US-6342570-B1 COPOLYMERIZING VINYL LACTAM AND VINYL MONOMER; METERING IN SECOND MONOMER MIXTURE; STATISTICALLY DISTRIBUTED BUILDING BLOCKS IN ACCORD WITH LEWIS-MAYO EQUATION; CURABLE NOVARTIS AG (CH) 2002-01-29 US disclosed
US-5936052-A Cross-linkable copolymers and hydrogels CIBA VISION CORPORATION (US) 1999-08-10 US disclosed
WO-1995000560-A1 REACTIVE POLYMERS JOHNSON, Karen, L. (US) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291831-A1 SEMICARBAZIDE COMPOSITION, METHOD FOR PRODUCING SEMICARBAZIDE COMPOSITION, AQUEOUS POLYMER COMPOSITION AND COMPOSITE C9, C5, BRD2 LMNA 1640/4885TFPI2 3328/4885GMNN 2676/4885
US-10023760-B2 Semicarbazide composition, method for producing semicarbazide composition, aqueous polymer composition and composite C9, C5, BRD2 LMNA 1640/4885TFPI2 3328/4885GMNN 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.