Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.37 |
| ▸ | ADK | P55263 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991287 | 0.87 | FLT3 (0.40) | SRCFLT3LCKTEKRET | |
| SCHEMBL8990936 | 0.85 | ADK (0.33) | SRCEGFRFLT3ADK | |
| SCHEMBL7700982 | 0.79 | FLT3 (0.37) | SRCKDREGFRFLT3ADK | |
| SCHEMBL8991302 | 0.77 | ADORA2A (0.49) | SRCKDREGFRFLT3LCK | |
| SCHEMBL8991031 | 0.77 | KDM4E (0.41) | SRCKDREGFRFLT3LCK | |
| SCHEMBL7700980 | 0.77 | NPC1 (0.45) | SRCKDREGFRFLT3ADK | |
| SCHEMBL7703236 | 0.77 | ADK (0.38) | SRCKDREGFRFLT3ADK | |
| SCHEMBL8991135 | 0.76 | KDM4E (0.35) | SRCKDREGFRFLT3ADK | |
| SCHEMBL8991256 | 0.75 | KDM4E (0.40) | SRCKDREGFRFLT3RET | |
| SCHEMBL8991275 | 0.74 | FLT3 (0.43) | SRCFLT3RETADORA2API4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |