Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991262 | 0.88 | ADK (0.35) | ADKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8991346 | 0.86 | PDE4A (0.40) | ADKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7703239 | 0.85 | SRC (0.38) | ADKFLT3EGFRSRC | |
| SCHEMBL7700322 | 0.80 | ADK (0.33) | ADKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8991397 | 0.80 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DFLT3 | |
| SCHEMBL8991078 | 0.78 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7700319 | 0.78 | EGFR (0.32) | ADKP2RY1EGFRSRCALDH1A1 | |
| SCHEMBL8990926 | 0.78 | EGFR (0.32) | ADKP2RY1EGFRSRC | |
| SCHEMBL8991143 | 0.78 | HDAC1 (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8991176 | 0.78 | XDH (0.31) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |