Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 9/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700980 | 0.87 | NPC1 (0.45) | ADKSRCLCKTEKEGFR | |
| SCHEMBL8991281 | 0.86 | ENPP1 (0.39) | SRCLCKTEKFLT3RET | |
| SCHEMBL8990926 | 0.84 | EGFR (0.32) | ADKSRCEGFR | |
| SCHEMBL8991270 | 0.82 | IGF1R (0.43) | SRCLCKTEKEGFRKDR | |
| SCHEMBL7700982 | 0.77 | FLT3 (0.37) | ADKSRCLCKTEKEGFR | |
| SCHEMBL7703239 | 0.77 | SRC (0.38) | ADKSRCLCKTEKEGFR | |
| SCHEMBL7695926 | 0.75 | ADK (0.45) | ADKSRCLCKTEKEGFR | |
| SCHEMBL8991019 | 0.75 | KDM4E (0.41) | SRCLCKTEKEGFRKDR | |
| SCHEMBL8991089 | 0.75 | EGFR (0.45) | SRCLCKTEKEGFRKDR | |
| SCHEMBL8991124 | 0.74 | PI4KB (0.35) | ADKSRCEGFRKDRPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |