Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703319 | 1.00 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL7703440 | 0.90 | FNTA (0.53) | FNTAFNTB | |
| SCHEMBL7703436 | 0.90 | FNTA (0.53) | FNTAFNTB | |
| SCHEMBL7709322 | 0.87 | CA2 (0.39) | FNTAFNTB | |
| SCHEMBL7709317 | 0.87 | CA2 (0.39) | FNTAFNTB | |
| SCHEMBL7241306 | 0.84 | MEN1 (0.35) | FNTAFNTB | |
| SCHEMBL7241309 | 0.84 | MEN1 (0.35) | FNTAFNTB | |
| SCHEMBL8227729 | 0.83 | KMT2A (0.33) | — | |
| SCHEMBL8227733 | 0.83 | KMT2A (0.33) | — | |
| SCHEMBL8207394 | 0.82 | FNTA (0.39) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | claimed |
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |