Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | LPL | P06858 | 3/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.43 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736 | 0.80 | TRPV1 (0.66) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL1706121 | 0.79 | PDE2A (0.62) | PDE2ATSHR | |
| SCHEMBL722182 | 0.78 | MGLL (0.56) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL24335819 | 0.76 | MGLL (0.67) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL2558888 | 0.76 | TAAR1 (0.54) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL25413876 | 0.76 | MGLL (0.79) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL4179 | 0.75 | MGLL (1.00) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL257878 | 0.74 | TRPV1 (0.59) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL5510327 | 0.74 | TRPV1 (0.59) | MGLLENPP2CA2LPLLIPG | |
| SCHEMBL28120485 | 0.74 | TRPV1 (0.59) | MGLLENPP2CA2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143365-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |