Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.45 |
| ▸ | FNTB | P49356 | 4/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708877 | 0.84 | NPC1 (0.41) | FNTAFNTBPGGT1BCYP3A4CYP2D6 | |
| SCHEMBL8198609 | 0.83 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL7240383 | 0.82 | FNTA (0.41) | FNTAFNTBPGGT1BAGTR2CYP3A4 | |
| SCHEMBL8383788 | 0.77 | FNTA (0.45) | FNTAFNTBPGGT1BAGTR2CYP3A4 | |
| SCHEMBL8205752 | 0.77 | FNTA (0.45) | FNTAFNTBPGGT1BAGTR2CYP3A4 | |
| SCHEMBL7659533 | 0.75 | CYP51A1 (0.46) | FNTAFNTBPGGT1BCYP3A4CYP2D6 | |
| SCHEMBL7563466 | 0.72 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL7562210 | 0.72 | FNTA (0.41) | FNTAFNTBPGGT1BCYP3A4CYP2D6 | |
| SCHEMBL7709034 | 0.71 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL6777942 | 0.70 | FNTA (0.65) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |