Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396674 | 1.00 | MGAM (0.40) | MGAMGAASIMGAM2 | |
| SCHEMBL27591903 | 0.81 | MGAM (0.40) | MGAMGAASIMGAM2 | |
| SCHEMBL16230001 | 0.81 | NAAA (0.35) | — | |
| SCHEMBL4326496 | 0.80 | ALDH1A1 (0.37) | GAA | |
| SCHEMBL13596594 | 0.80 | ALDH1A1 (0.37) | GAA | |
| SCHEMBL27098403 | 0.79 | — | — | |
| SCHEMBL27657768 | 0.77 | MGAM (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL6445001 | 0.76 | MGAM (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL5227698 | 0.76 | MGAM (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL6444996 | 0.76 | MGAM (0.46) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-208726934-U | One kind is for producing 4,4,4- trifluorobutene acetoacetic ester centrifugation Multistage filtering device | 南京齐正化学有限公司 | 2019-04-12 | — | — | CN | claimed |
| CN-103113249-B | Synthetic method of 3-amino-4,4,4-trifluorine ethyl crotonate | SHANGYU SUNFIT CHEMICAL CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-208726934-U | One kind is for producing 4,4,4- trifluorobutene acetoacetic ester centrifugation Multistage filtering device | 南京齐正化学有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-208726934-U | One kind is for producing 4,4,4- trifluorobutene acetoacetic ester centrifugation Multistage filtering device | 南京齐正化学有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-208726934-U | One kind is for producing 4,4,4- trifluorobutene acetoacetic ester centrifugation Multistage filtering device | 南京齐正化学有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-109096108-A | The synthetic method of 4,4,4- trifluorobutene acid esters | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-108290881-A | Therapeutic compounds and methods of use thereof | 健泰科生物技术公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-103119038-B | As 4-(5-isoxazolyl or 5-pyrazolyl-1,2, the 4-oxadiazolyl-3-yl) mandelic acidamide of S1P 1 receptor stimulating agent | BRISTOL-MYERS SQUIBB CO. (US) | 2016-05-04 | — | — | CN | disclosed |
| CN-103113249-B | Synthetic method of 3-amino-4,4,4-trifluorine ethyl crotonate | SHANGYU SUNFIT CHEMICAL CO LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-103298807-A | Heterocyclic compounds as S1P1 agonists for the treatment of autoimmune and vascular diseases | BRISTOL MYERS SQUIBB CO | 2013-09-11 | — | — | CN | disclosed |
| CN-103119038-A | 4 - (5 - isoxazolyl or 5 - pyrrazolyl -1,2,4- oxadiazol - 3 - yl) -mandelic acid amides as sphingosin- 1 - phosphate 1 rreceptor agonists | BRISTOL MYERS SQUIBB CO | 2013-05-22 | — | — | CN | disclosed |
| CN-102548989-A | Sphingosine-1-phosphate receptor agonists | BRISTOL MYERS SQUIBB CO | 2012-07-04 | — | — | CN | disclosed |
| US-6498180-B1 | SUCH AS 2-(3'-HYDROXYMETHYL-2'-CARBOXYCYCLOPROPYL)GLYCINE; MODULATING METABOTROPIC GLUTAMATE RECEPTOR; TREATING DISORDERS OF CENTRAL NERVOUS | ELI LILLY AND COMPANY | 2002-12-24 | — | — | US | disclosed |