SCHEMBL7703547

SCHEMBL7703547

O=C(NCCc1ccccc1)c1cc(Cl)nnc1Cl

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.61
NPC1 O15118 5/20 0.61
TAAR1 Q96RJ0 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.54
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.53
KMT2A Q03164 1/20 0.52
CASP1 P29466 1/20 0.51
POLB P06746 1/20 0.50
KDM4E B2RXH2 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31683856 1.00 RAB9A (0.61) RAB9ANPC1TAAR1SMN1; SMN2LMNA
SCHEMBL31622388 0.89 MAPT (0.57) RAB9ANPC1SMN1; SMN2LMNAMAPT
SCHEMBL31683858 0.88 SMN1; SMN2 (0.58) RAB9ANPC1TAAR1SMN1; SMN2LMNA
SCHEMBL28631718 0.88 SMN1; SMN2 (0.58) RAB9ANPC1TAAR1SMN1; SMN2LMNA
SCHEMBL28633296 0.88 NPC1 (0.55) RAB9ANPC1SMN1; SMN2LMNAMAPT
SCHEMBL31683863 0.86 NPC1 (0.49) RAB9ANPC1SMN1; SMN2LMNAMAPT
SCHEMBL28635932 0.86 NPC1 (0.49) RAB9ANPC1SMN1; SMN2LMNAMAPT
SCHEMBL31683854 0.86 CNR1 (0.52) RAB9ANPC1TAAR1SMN1; SMN2LMNA
SCHEMBL28636200 0.86 CNR1 (0.52) RAB9ANPC1TAAR1SMN1; SMN2LMNA
SCHEMBL31683859 0.86 SMN1; SMN2 (0.53) RAB9ANPC1TAAR1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3887362-B1 PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AG (DE) 2025-06-18 EP disclosed
EP-0901488-B1 2,4-DIAMINOPYRIMIDINE DERIVATIVES BASILEA PHARMACEUTICA AG (CH) 2002-11-06 EP disclosed
US-5866583-A Substituted 2,4-diaminopyrimidines HOFFMANN-LA ROCHE INC. (US) 1999-02-02 US disclosed