Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31683863 | 1.00 | NPC1 (0.49) | NPC1RAB9ACNR1CNR2SMN1; SMN2 | |
| SCHEMBL31622388 | 0.89 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28633296 | 0.88 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL28638483 | 0.88 | ALDH1A1 (0.40) | NPC1RAB9ACNR1CNR2SMN1; SMN2 | |
| SCHEMBL31683855 | 0.88 | ALDH1A1 (0.40) | NPC1RAB9ACNR1CNR2SMN1; SMN2 | |
| SCHEMBL31683856 | 0.86 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL7703547 | 0.86 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL31683854 | 0.86 | CNR1 (0.52) | NPC1RAB9ACNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28636200 | 0.86 | CNR1 (0.52) | NPC1RAB9ACNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31683865 | 0.84 | KMT2A (0.64) | CNR2SMN1; SMN2ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490663-A | Pyridazine (thio) amides as fungicidal compounds | 拜耳公司 | 2021-10-08 | — | — | CN | disclosed |