Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511328 | 0.80 | ALOX5 (0.36) | — | |
| SCHEMBL19926140 | 0.73 | CPN1 (0.33) | — | |
| SCHEMBL14616651 | 0.72 | CA2 (0.35) | — | |
| SCHEMBL29174838 | 0.71 | ALOX5 (0.40) | — | |
| SCHEMBL29187952 | 0.71 | ALOX5 (0.31) | — | |
| SCHEMBL11812961 | 0.70 | EPHX1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL29172438 | 0.70 | ALOX5 (0.39) | — | |
| SCHEMBL6098104 | 0.69 | EPHX1 (0.46) | — | |
| SCHEMBL16161331 | 0.68 | THRB (0.46) | — | |
| SCHEMBL28749516 | 0.67 | CA2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348616-B1 | CHEMICAL INTERMEDIATES FOR SYNTHESIS OF DESIRED BENZOXAZINONES | PIERCE MICHAEL ERNEST (US) | 2002-02-19 | — | — | US | disclosed |
| US-6147210-A | Practical synthesis of benzoxazinones useful as HIV reverse transcriptase inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| WO-1998004535-A1 | A PRACTICAL SYNTHESIS OF BENZOXAZINONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |