Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | LCT | P09848 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942354 | 0.88 | S1PR1 (0.43) | S1PR1TDP1S1PR3 | |
| SCHEMBL27638657 | 0.86 | CSNK2A1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL3898700 | 0.81 | PDK2 (0.47) | S1PR1MMP2MMP3RORCS1PR3 | |
| SCHEMBL7461260 | 0.80 | SLC13A5 (0.53) | TDP1SLC13A5 | |
| SCHEMBL6673882 | 0.80 | CSNK2A1 (0.57) | S1PR1RORCS1PR3GBA1LCT | |
| SCHEMBL7368161 | 0.80 | RORC (0.48) | S1PR1MMP2MMP3RORCS1PR3 | |
| SCHEMBL27384582 | 0.79 | TDP1 (0.52) | TDP1 | |
| SCHEMBL11192457 | 0.78 | TDP1 (0.47) | TDP1 | |
| SCHEMBL11831544 | 0.78 | MMP2 (0.47) | S1PR1MMP2MMP3RORCS1PR3 | |
| SCHEMBL27942311 | 0.77 | RORC (0.44) | S1PR1MMP2MMP3RORCS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216996-A2 | Method to synthesise biphenylyl derivatives | SANOFI-SYNTHELABO (FR) | 2002-06-26 | — | — | EP | disclosed |
| EP-0837848-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001536-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1997-01-16 | — | — | WO | disclosed |
| CN-1066070-A | Promote the new benzo-fused lactams that tethelin discharges | MERCK & CO INC (US) | 1992-11-11 | — | — | CN | disclosed |