Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | LCT | P09848 | 2/20 | 0.40 |
| ▸ | UGCG | Q16739 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12141580 | 0.85 | KIF11 (0.53) | RORCPDK2S1PR1AKR1C3AKR1C2 | |
| SCHEMBL3898700 | 0.84 | PDK2 (0.47) | RORCPDK2S1PR1S1PR3MMP2 | |
| SCHEMBL6673882 | 0.83 | CSNK2A1 (0.57) | RORCS1PR1S1PR3GBA1LCT | |
| SCHEMBL12142103 | 0.82 | AKR1C3 (0.63) | NPC1ALDH1A1RAB9ASMN1; SMN2S1PR1 | |
| SCHEMBL7703690 | 0.80 | S1PR1 (0.44) | RORCS1PR1S1PR3MMP2MMP3 | |
| SCHEMBL27942311 | 0.80 | RORC (0.44) | RORCS1PR1AKR1C3AKR1C2S1PR3 | |
| Methyl Alcohol SCHEMBL3902225 | 0.80 | RORC (0.44) | RORCS1PR1AKR1C3AKR1C2MMP2 | |
| SCHEMBL24910198 | 0.79 | PDK2 (0.42) | RORCPDK2NPC1ALDH1A1LMNA | |
| SCHEMBL21753831 | 0.79 | PSEN1 (0.60) | RORCLMNAS1PR1S1PR3WNT3A | |
| SCHEMBL28160375 | 0.79 | RORC (0.43) | RORCS1PR1S1PR3MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254250-A | Ferrocenyl pyridine cyclic Pd-N heterocyclic carbene compound as well as preparation method and application thereof | UNIV LUOYANG NORMAL | 2013-08-21 | — | — | CN | disclosed |
| EP-1873153-B1 | 3-AZETIDINECARBOXYLIC ACID DERIVATIVES FOR USE AS IMMUNOSUPPRESSANTS | DAIICHI SANKYO CO LTD (JP) | 2010-07-07 | — | — | EP | disclosed |
| CN-1153765-C | 4-aryl-1-phenylalkyl-1, 2,3, 6-tetrahydropyridines having neurotrophic and protective activity | ��ŵ�Ѻϳ�ʵ���� | 2004-06-16 | — | — | CN | disclosed |
| US-6344464-B1 | Use of tetrahydropyridine derivatives to prepare medicines for treating diseases causing demyelination | SANOFI-SYNTHELABO (FR) | 2002-02-05 | — | — | US | disclosed |
| CN-1189154-A | 4-aryl-1-phenylalkyl-1,2,3,6-Tetrahydropyridines having neurotrophic and neuroprotective activity | SANOFI SA (FR) | 1998-07-29 | — | — | CN | disclosed |