Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700202 | 0.92 | EPHX2 (0.52) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL7699756 | 0.91 | EPHX2 (0.48) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL7701384 | 0.87 | EPHX2 (0.51) | ALDH1A1SMN1; SMN2HPGDCYP1A2CYP3A4 | |
| SCHEMBL7700128 | 0.87 | EPHX2 (0.49) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7701450 | 0.86 | EPHX2 (0.48) | ALDH1A1SMN1; SMN2MAPTGAANPSR1 | |
| SCHEMBL7693795 | 0.85 | KDM4E (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7701962 | 0.85 | TAOK1 (0.54) | SMN1; SMN2MAPTPOLBEPHX2DGAT1 | |
| SCHEMBL7705421 | 0.85 | CNR1 (0.50) | TRPV1EPHX2PTGESCNR1CNR2 | |
| SCHEMBL7696456 | 0.85 | MAPT (0.51) | RAB9ALMNAMAPTMEN1KMT2A | |
| SCHEMBL7693770 | 0.84 | TSHR (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |