Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRK3 | P35626 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | GRK2 | P25098 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700202 | 0.92 | EPHX2 (0.52) | EPHX2PPARGTP53PTGESMEN1 | |
| SCHEMBL7701450 | 0.91 | EPHX2 (0.48) | EPHX2PPARGTP53MAPTSMN1; SMN2 | |
| SCHEMBL7701384 | 0.91 | EPHX2 (0.51) | EPHX2PPARGTP53MAPTSMN1; SMN2 | |
| SCHEMBL7693770 | 0.89 | TSHR (0.50) | EPHX2TP53MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7699756 | 0.87 | EPHX2 (0.48) | EPHX2MAPTSMN1; SMN2PTGESGRK3 | |
| SCHEMBL7703699 | 0.87 | ALDH1A1 (0.51) | EPHX2MAPTSMN1; SMN2PTGESMEN1 | |
| SCHEMBL7696332 | 0.86 | PTGES (0.49) | EPHX2TP53MAPTSMN1; SMN2PTGES | |
| SCHEMBL7693795 | 0.85 | KDM4E (0.51) | EPHX2TP53SMN1; SMN2PTGESMEN1 | |
| SCHEMBL7701962 | 0.85 | TAOK1 (0.54) | EPHX2PPARGTP53MAPTSMN1; SMN2 | |
| SCHEMBL7696456 | 0.85 | MAPT (0.51) | EPHX2TP53MAPTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |