Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764006 | 0.79 | GPR119 (0.39) | KMT2AGPR119KLK7KLK5 | |
| SCHEMBL9764011 | 0.79 | GPR119 (0.39) | KMT2AGPR119KLK7KLK5 | |
| SCHEMBL12824561 | 0.77 | HSD17B10 (0.36) | MAPTNPC1ALDH1A1MAPK1HTT | |
| SCHEMBL7697794 | 0.76 | KLK7 (0.39) | MEN1KMT2AKLK7KLK5 | |
| SCHEMBL7697791 | 0.76 | KLK7 (0.39) | MEN1KMT2AKLK7KLK5 | |
| SCHEMBL7703728 | 0.75 | NR1H2 (0.38) | MEN1KMT2AKLK7 | |
| SCHEMBL9763248 | 0.74 | ACE (0.42) | MAPK1L3MBTL1KMT2AGPR119KLK7 | |
| SCHEMBL9763781 | 0.74 | HTRA1 (0.34) | MAPTNPC1ALDH1A1MAPK1HTT | |
| SCHEMBL9763782 | 0.74 | HTRA1 (0.34) | MAPTNPC1ALDH1A1MAPK1HTT | |
| SCHEMBL10434897 | 0.72 | HSD17B2 (0.39) | L3MBTL1KMT2AGPR119KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |