Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699757 | 0.83 | HDAC4 (0.34) | HDAC4HDAC7HDAC5DRD2LMNA | |
| SCHEMBL2996951 | 0.74 | HDAC4 (0.44) | HDAC4HDAC7HDAC5DRD2MEN1 | |
| SCHEMBL7796551 | 0.73 | HDAC4 (0.32) | HDAC4HDAC7HDAC5DRD2MEN1 | |
| SCHEMBL7795307 | 0.73 | KMT2A (0.34) | HDAC4HDAC7HDAC5DRD2MEN1 | |
| SCHEMBL7703633 | 0.72 | PGR (0.41) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL7793796 | 0.71 | ALDH1A1 (0.33) | HDAC4HDAC7HDAC5DRD2MEN1 | |
| SCHEMBL5705543 | 0.70 | DRD2 (0.39) | HDAC4HDAC7HDAC5DRD2DRD1 | |
| SCHEMBL6256438 | 0.69 | DRD2 (0.38) | HDAC4HDAC7HDAC5DRD2MEN1 | |
| SCHEMBL7796579 | 0.69 | DRD2 (0.38) | HDAC4HDAC7HDAC5DRD2MEN1 | |
| SCHEMBL7793782 | 0.69 | DRD2 (0.36) | HDAC4HDAC7HDAC5DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |