Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7703952

COc1ccc2c(c1)c(C(=O)OC(F)(C(F)F)C(F)(F)F)c1cc(OC)ccc1[n+]2C.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.36
ACHE P22303 6/20 0.34
PPM1A P35813 1/20 0.33
HSP90AA1 P07900 1/20 0.33
G6PD P11413 1/20 0.33
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
TRPV1 Q8NER1 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
HSD11B1 P28845 1/20 0.31
CNR1 P21554 1/20 0.31
AR P10275 1/20 0.30
PTGS1 P23219 1/20 0.30
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
MAPT P10636 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL7703955 0.84 ABHD6 (0.40) KCNH2ACHEPPM1AHSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL7703830 0.84 ACHE (0.34) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7702813 0.84 ACHE (0.33) KCNH2ACHEHSP90AA1
Trifluoromethanesulfonic Acid SCHEMBL7702380 0.83 ACHE (0.31) ACHE
Trifluoromethanesulfonic Acid SCHEMBL7706736 0.82 KCNH2 (0.33) KCNH2
Trifluoromethanesulfonic Acid SCHEMBL38662582 0.78 KCNH2 (0.37) KCNH2ACHEPPM1AHSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL8740677 0.78 KCNH2 (0.41) KCNH2ACHEPPM1AHSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL38661828 0.78 KCNH2 (0.36) KCNH2ACHEPPM1AHSP90AA1G6PD
Trifluoromethanesulfonic Acid SCHEMBL38661531 0.77 KCNH2 (0.39) KCNH2ACHETRPV1
Trifluoromethanesulfonic Acid SCHEMBL7793210 0.77 ACHE (0.37) KCNH2ACHEPPM1AHSP90AA1G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915851-B1 DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS NEDERLANDEN STAAT (NL) 2002-03-20 EP disclosed