Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704043 | 0.78 | SLC6A4 (0.45) | LMNA | |
| SCHEMBL10892146 | 0.74 | GAA (0.40) | L3MBTL1GAAOPRL1 | |
| SCHEMBL4862021 | 0.72 | KMT2A (0.39) | OPRL1OPRK1RECQLLMNAHPGD | |
| SCHEMBL4789001 | 0.71 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL17086664 | 0.70 | OPRM1 (0.47) | OPRL1OPRM1OPRK1OPRD1LMNA | |
| SCHEMBL17086655 | 0.70 | OPRM1 (0.47) | OPRL1OPRM1OPRK1OPRD1LMNA | |
| SCHEMBL19494132 | 0.70 | OPRM1 (0.47) | OPRL1OPRM1OPRK1OPRD1LMNA | |
| SCHEMBL17086666 | 0.70 | OPRM1 (0.47) | OPRL1OPRM1OPRK1OPRD1LMNA | |
| SCHEMBL17086651 | 0.70 | OPRM1 (0.47) | OPRL1OPRM1OPRK1OPRD1LMNA | |
| SCHEMBL17086668 | 0.69 | OPRM1 (0.50) | OPRL1OPRM1OPRK1OPRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452074-B1 | Ergoline-8-carboxamides for blocking 5HT receptors | LILLY CO ELI (US) | 1996-01-24 | — | — | EP | disclosed |