Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822075 | 0.90 | CHEK1 (0.44) | CHRM3CHEK1 | |
| SCHEMBL7700703 | 0.81 | CHEK1 (0.53) | CHEK1 | |
| SCHEMBL7814577 | 0.81 | CHEK1 (0.57) | CHEK1 | |
| SCHEMBL7093375 | 0.79 | CHEK1 (0.50) | CHEK1 | |
| SCHEMBL7835370 | 0.79 | CHEK1 (0.51) | CHRM3CHEK1 | |
| SCHEMBL7165696 | 0.79 | CHEK1 (0.49) | CHEK1 | |
| SCHEMBL7701289 | 0.78 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL7698793 | 0.77 | RAB9A (0.48) | CHEK1 | |
| SCHEMBL7696212 | 0.77 | CHEK1 (0.47) | CHEK1 | |
| Acetic Acid SCHEMBL7701547 | 0.77 | KDR (0.48) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462036-B1 | INHIBITING SIGNAL TRANSDUCTION BY MODULATING ACTIVITY OF RECEPTOR AND NONRECEPTOR TYROSINE AND SERINE/THREONINE KINASES TO REGULATE AND MODULATE ABNORMAL OR INAPPROPRIATE CELL PROLIFERATION, DIFFERENTIATION, OR METABOLISM | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |