Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 11/20 | 0.49 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CALML3 | P27482 | 1/20 | 0.46 |
| ▸ | SDHA | P31040 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10162640 | 0.79 | F10 (0.47) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7712716 | 0.79 | ABCB11 (0.58) | ABCB11F10MAOAMAOBLMNA | |
| SCHEMBL6211080 | 0.78 | MAOA (0.48) | F10MAOAMAOBLMNAPTGS1 | |
| Dup-721 SCHEMBL9521400 | 0.78 | ABCB11 (0.59) | ABCB11F10MAOAMAOBLMNA | |
| Dup-721 SCHEMBL4402113 | 0.78 | ABCB11 (0.59) | ABCB11F10MAOAMAOBLMNA | |
| SCHEMBL27951203 | 0.78 | F10 (0.64) | ABCB11F10MAOAMAOBLMNA | |
| SCHEMBL6097066 | 0.78 | F10 (0.64) | ABCB11F10MAOAMAOBLMNA | |
| SCHEMBL16281089 | 0.78 | F10 (0.43) | ABCB11F10MAOAMAOBLMNA | |
| SCHEMBL9671417 | 0.77 | ABCB11 (0.59) | ABCB11F10MAOAMAOBLMNA | |
| SCHEMBL8991492 | 0.77 | MAOA (0.54) | ABCB11F10MAOAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362191-B1 | ANTIBIOTICS | ZENECA LTD. (GB) | 2002-03-26 | — | — | US | disclosed |
| EP-1007525-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999011642-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-03-11 | — | — | WO | disclosed |