Dup-721

Dup-721

SCHEMBL4402113

CC(=O)NC[C@H]1CN(c2ccc(C(C)=O)cc2)C(=O)O1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.59
MAOA P21397 5/20 0.59
MAOB P27338 2/20 0.59
LMNA P02545 1/20 0.59
PTGS1 P23219 1/20 0.59
CALML3 P27482 1/20 0.59
SDHA P31040 1/20 0.59
F10 P00742 7/20 0.57
ITGB3 P05106 2/20 0.53
PRSS1 P07477 2/20 0.53
PRSS2 P07478 2/20 0.53
ITGA2B P08514 2/20 0.53
PRSS3 P35030 2/20 0.53
GRM2 Q14416 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dup-721 SCHEMBL9521400 1.00 ABCB11 (0.59) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL9550268 0.96 ABCB11 (0.56) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL9550285 0.96 ABCB11 (0.56) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL13298924 0.90 MAOA (0.61) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL10753981 0.89 F10 (0.57) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL16703808 0.88 MAOA (0.60) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL9550292 0.88 MAOA (0.60) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL15367964 0.88 MAOA (0.60) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL9815521 0.88 F10 (0.50) ABCB11MAOAMAOBLMNAPTGS1
SCHEMBL7710474 0.88 ABCB11 (0.55) ABCB11MAOAMAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048106-A1 IMMUNOTHERAPY TARGETING TUMOR TRANSPOSABLE ELEMENT DERIVEDNEOANTIGENIC PEPTIDES IN GLIOBLASTOMA INST CURIE (FR) 2026-02-19 US disclosed
US-20250302930-A1 IMMUNOTHERAPY TARGETING TUMOR TRANSPOSABLE ELEMENT DERIVED NEOANTIGENIC PEPTIDES IN GLIOBLASTOMA LNSTITUT GUSTAVE-ROUSSY (FR) 2025-10-02 US disclosed
CN-115466253-B Oxazolidinone compound containing dithiocarbamic acid ester structure and preparation method thereof 沈阳药科大学 2024-08-20 CN disclosed
CN-117904087-A Halohydrin dehalogenase mutant and application thereof in preparation of chiral oxazolidinone 中国科学院天津工业生物技术研究所 2024-04-19 CN disclosed
CN-115677679-A Oxazolidinone compound containing biaryl hydrazone structure and preparation method and application thereof 沈阳药科大学 2023-02-03 CN disclosed
CN-115466253-A Oxazolidinone compound containing dithiocarbamate structure and preparation method thereof 沈阳药科大学 2022-12-13 CN disclosed
US-20210121449-A1 NOVEL OXAZOLIDINONE DERIVATIVES DONG A ST CO LTD (KR) 2021-04-29 US disclosed
US-20170333414-A1 NOVEL OXAZOLIDINONE DERIVATIVES DONG A ST CO LTD (KR) 2017-11-23 US disclosed
US-20170049763-A1 NOVEL OXAZOLIDINONE DERIVATIVES DONG A ST CO LTD (KR) 2017-02-23 US disclosed
US-9163043-B2 Oxazolidinone derivatives DONG-A ST CO., LTD. (KR) 2015-10-20 US disclosed
WO-2010032901-A1 NOVEL OXAZOLIDINONE DERIVATIVE WITH DIFLUOROPHENYL MOIETY, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF AND ANTIBIOTIC COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-03-25 WO disclosed
US-20100069449-A1 NOVEL OXAZOLIDINONE DERIVATIVE WITH DIFLUOROPHENYL MOIETY, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF AND ANTIBIOTIC COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-18 US disclosed
US-20100069449-A1 NOVEL OXAZOLIDINONE DERIVATIVE WITH DIFLUOROPHENYL MOIETY, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF AND ANTIBIOTIC COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-18 US disclosed
US-20100063117-A1 Novel oxazolidinone derivative with difluorophenyl moiety, pharmaceutically acceptable salt thereof, preparation method thereof and antibiotic composition containing the same as an active ingredient KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20100063117-A1 Novel oxazolidinone derivative with difluorophenyl moiety, pharmaceutically acceptable salt thereof, preparation method thereof and antibiotic composition containing the same as an active ingredient KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20090192197-A1 Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes Torezolid phosphate DONG-A PHARM. CO., LTD. (KR) 2009-07-30 US disclosed
US-20090192197-A1 Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes Torezolid phosphate DONG-A PHARM. CO., LTD. (KR) 2009-07-30 US disclosed
WO-2008127025-A1 A NOVEL HETEROCYCLE OR ALKOXYAMINOMETHYL OXAZOLIDINONE DERIVATIVE AND MANUFACTURING PROCESS THEREOF ILDONG PHARMACEUTICAL CO., LTD (KR) 2008-10-23 WO disclosed
US-20070155798-A1 Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes torezolid phosphate DONG-A PHARM. CO., LTD. 2007-07-05 US disclosed
US-20070155798-A1 Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes torezolid phosphate DONG-A PHARM. CO., LTD. 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170049763-A1 NOVEL OXAZOLIDINONE DERIVATIVES ALPI, OXA1L, SI ABCB11 193/4885MAOA 2505/4885MAOB 1905/4885
US-20100063117-A1 Novel oxazolidinone derivative with difluorophenyl moiety, pharmaceutically acceptable salt thereof, preparation method thereof and antibiotic composition containing the same as an active ingredient VRK1, ALPI, VRK2 ABCB11 179/4885MAOA 2024/4885MAOB 1898/4885
US-20260048106-A1 IMMUNOTHERAPY TARGETING TUMOR TRANSPOSABLE ELEMENT DERIVEDNEOANTIGENIC PEPTIDES IN GLIOBLASTOMA MICA, TAP1, TNFSF10 ABCB11 4359/4885MAOA 4637/4885MAOB 4620/4885
US-20210121449-A1 NOVEL OXAZOLIDINONE DERIVATIVES ALPI, OXA1L, SI ABCB11 193/4885MAOA 2505/4885MAOB 1905/4885
US-20070155798-A1 Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes torezolid phosphate ALPI, SI, TST ABCB11 278/4885MAOA 4398/4885MAOB 4248/4885
US-20090192197-A1 Antibiotics with improved solubility, lower toxicity; potent antibacterial activity; includes Torezolid phosphate ALPI, TPI1, SI ABCB11 425/4885MAOA 3819/4885MAOB 3591/4885
US-20100069449-A1 NOVEL OXAZOLIDINONE DERIVATIVE WITH DIFLUOROPHENYL MOIETY, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF AND ANTIBIOTIC COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT VRK1, ALPI, VRK2 ABCB11 179/4885MAOA 2024/4885MAOB 1898/4885
US-20170333414-A1 NOVEL OXAZOLIDINONE DERIVATIVES ALPI, OXA1L, SI ABCB11 193/4885MAOA 2505/4885MAOB 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.