SCHEMBL7704460

SCHEMBL7704460

CCCC(S)C(=O)OC(=O)C(S)CCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
CYP3A4 P08684 2/20 0.37
TSHR P16473 2/20 0.37
NFKB1 P19838 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ALDH1A1 P00352 4/20 0.35
SOAT1 P35610 1/20 0.35
HDAC7 Q8WUI4 2/20 0.34
HDAC8 Q9BY41 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2145419 0.88
SCHEMBL2134188 0.85 ALDH1A1 (0.43) HDAC1HDAC2TDP1CHRM1AKR1A1
SCHEMBL2131658 0.83
SCHEMBL2135231 0.83 HDAC1 (0.39) HDAC1HDAC2TDP1CHRM1AKR1A1
SCHEMBL29091247 0.83
SCHEMBL7704462 0.82 TSHR (0.42) TDP1CYP3A4TSHRALDH1A1LMNA
SCHEMBL2134483 0.79 ALDH1A1 (0.52) TDP1TSHRALDH1A1CA1CA2
SCHEMBL10577271 0.79 HDAC1 (0.34) HDAC1HDAC2TDP1CHRM1AKR1A1
SCHEMBL2136099 0.79 TSHR (0.42) HDAC1HDAC2TDP1CHRM1AKR1A1
SCHEMBL11601336 0.79 HDAC1 (0.34) HDAC1HDAC2TDP1CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361872-B1 CORROSION RESISTANCE FOR METAL SURFACES WITH MERCAPTO COMPOUNDS AND CURING AGENTS METAL COATINGS INTERNATIONAL INC. 2002-03-26 US disclosed
WO-1999060187-A1 METAL SURFACE TREATMENT AGENTS, METHODS OF TREATING METAL SURFACES AND PRE-COATED STEEL SHEETS DACRAL S.A. (FR) 1999-11-25 WO disclosed