SCHEMBL2134188

SCHEMBL2134188

CCCC(S)C(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 2/20 0.41
ALOX15 P16050 1/20 0.40
CPB2 Q96IY4 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2136038 0.86 CA2 (0.45) ALDH1A1LMNAHSD17B10POLBALOX15
SCHEMBL7704460 0.85 HDAC1 (0.39) ALDH1A1LMNASOAT1CHRM1AKR1A1
SCHEMBL2136155 0.84 ZDHHC7 (0.46) CPB2CA1CA2
SCHEMBL2131658 0.83
SCHEMBL2135231 0.83 HDAC1 (0.39) ALDH1A1LMNACHRM1AKR1A1CHRM3
SCHEMBL2145419 0.83
SCHEMBL6809900 0.83 CPB2 (0.43) ALDH1A1LMNAHSD17B10POLBALOX15
SCHEMBL29091247 0.83
SCHEMBL9554974 0.82 ZDHHC7 (0.48) CPB2CA2
SCHEMBL8648692 0.82 ZDHHC7 (0.48) CPB2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104768988-B Method for preparing thermoplastic resin composition having excellent surface clarity and gloss LG化学株式会社 2017-04-12 CN claimed
CN-104768988-A Method for preparing thermoplastic resin composition having excellent surface clarity and gloss LG CHEMICAL LTD 2015-07-08 CN claimed
US-11802172-B2 Composition for seeded polymerization, a seed copolymer and a method for preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-10-31 US disclosed
US-11692054-B2 Composition for seeded polymerization, a conjugated diene copolymer, an molded body, and a method for preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-07-04 US disclosed
US-20200199278-A1 COMPOSITION FOR SEEDED POLYMERIZATION, A CONJUGATED DIENE COPOLYMER, AN MOLDED BODY, AND A METHOD FOR PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-06-25 US disclosed
US-20200172648-A1 COMPOSITION FOR SEEDED POLYMERIZATION, A SEED COPOLYMER AND A METHOD FOR PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-06-04 US disclosed
CN-107501647-A Rubber composition and the pneumatic tire with the tyre surface formed by the rubber composition 住友橡胶工业株式会社 2017-12-22 CN disclosed
CN-104768988-B Method for preparing thermoplastic resin composition having excellent surface clarity and gloss LG化学株式会社 2017-04-12 CN disclosed
CN-105315523-A RUBBER COMPOSITION AND PNEUMATIC TIRE HAVING TREAD MANUFACTURED FROM SAID RUBBER COMPOSITION SUMITOMO RUBBER IND 2016-02-10 CN disclosed
CN-104768988-A Method for preparing thermoplastic resin composition having excellent surface clarity and gloss LG CHEMICAL LTD 2015-07-08 CN disclosed
CN-102471252-B Process for producing (fluoroalkylthio) acetic acid ester SUMITOMO CHEMICAL CO 2014-07-02 CN disclosed
US-20080015238-A1 CYCLOALKYLMETHOXY-SUBSTITUTED ACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-01-17 US disclosed
US-7259177-B2 Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-08-21 US disclosed
US-7259177-B2 Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-08-21 US disclosed
US-7259177-B2 Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-08-21 US disclosed
EP-1599452-B1 3-(2-PHENYL-OXAZOL-4-YL METHOXY) CYCLOHEXYLMETHOXY ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS USED AS PPAR MODULATORS FOR TREATING TYPE 2 DIABETES AND ARTERIOSCLEROSIS SANOFI AVENTIS DEUTSCHLAND (DE) 2007-06-20 EP disclosed
EP-1599452-B1 3-(2-PHENYL-OXAZOL-4-YL METHOXY) CYCLOHEXYLMETHOXY ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS USED AS PPAR MODULATORS FOR TREATING TYPE 2 DIABETES AND ARTERIOSCLEROSIS SANOFI AVENTIS DEUTSCHLAND (DE) 2007-06-20 EP disclosed
EP-1599452-A1 3-(2-PHENYL-OXAZOL-4-YL METHOXY) CYCLOHEXYLMETHOXY ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS USED AS PPAR MODULATORS FOR TREATING TYPE 2 DIABETES AND ARTERIOSCLEROSIS Sanofi-Aventis Deutschland GmbH (DE) 2005-11-30 EP disclosed
US-20050101637-A1 Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-05-12 US disclosed
WO-2004076427-A1 3-(2-PHENYL-OXAZOL-4-YL METHOXY) CYCLOHEXYLMETHOXY ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS USED AS PPAR MODULATORS FOR TREATING TYPE 2 DIABETES AND ARTERIOSCLEROSIS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080015238-A1 CYCLOALKYLMETHOXY-SUBSTITUTED ACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS GPR119, PC, ACADM ALDH1A1 268/4885LMNA 2818/4885HSD17B10 90/4885
US-20050101637-A1 Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals GPR119, PC, CPT1A ALDH1A1 212/4885LMNA 2609/4885HSD17B10 78/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.