Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19726540 | 0.89 | ATM (0.60) | KMT2AMEN1ALDH1A1ATM | |
| SCHEMBL8783690 | 0.89 | KMT2A (0.47) | KMT2AMEN1RECQLALDH1A1CYP2C19 | |
| SCHEMBL10334564 | 0.89 | POLB (0.48) | KMT2AMEN1RECQLALDH1A1CYP2C19 | |
| SCHEMBL17901116 | 0.89 | ATM (0.60) | KMT2AMEN1ALDH1A1ATM | |
| SCHEMBL10334714 | 0.85 | LMNA (0.50) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL14945154 | 0.85 | LMNA (0.51) | KMT2AMEN1RECQLALDH1A1CYP2C19 | |
| SCHEMBL27585390 | 0.85 | LMNA (0.51) | KMT2AMEN1RECQLALDH1A1CYP2C19 | |
| SCHEMBL1824721 | 0.84 | CA1 (0.50) | ALDH1A1ATM | |
| SCHEMBL16672466 | 0.84 | KMT2A (0.56) | KMT2AMEN1ALDH1A1PKMMMP8 | |
| SCHEMBL7704690 | 0.84 | ALDH1A1 (0.49) | KMT2AMEN1RECQLALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076466-B1 | MODULATORS OF CULLIN 3 ADAPTOR KBTBD4 AS ANTI-CANCER COMPOUNDS | UNIV MONTREAL (CA) | 2026-03-11 | — | — | EP | disclosed |
| US-20230073512-A1 | MODULATORS OF CULLIN 3 ADAPTOR KBTBD4 AS ANTI-CANCER COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2023-03-09 | — | — | US | disclosed |
| EP-4076466-A1 | MODULATORS OF CULLIN 3 ADAPTOR KBTBD4 AS ANTI-CANCER COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2022-10-26 | — | — | EP | disclosed |
| CN-114845719-A | Modulators of the CULLIN3 connexin kbbd 4 as anti-cancer compounds | 蒙特利尔大学 | 2022-08-02 | — | — | CN | disclosed |
| WO-2021119834-A1 | MODULATORS OF CULLIN 3 ADAPTOR KBTBD4 AS ANTI-CANCER COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021119834-A1 | MODULATORS OF CULLIN 3 ADAPTOR KBTBD4 AS ANTI-CANCER COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2021-06-24 | — | — | WO | disclosed |
| CN-109721586-A | A kind of 5- benzyl -3- pyridyl group -1H-1,2,4- triazole class compounds and its preparation method and application | 中国医科大学 | 2019-05-07 | — | — | CN | disclosed |
| CN-104292102-A | Preparation method for azoxystrobin intermediate | ZHEJIANG YINGXIN CHEMICAL CO LTD | 2015-01-21 | — | — | CN | disclosed |
| CN-1871228-A | A manufacturing process of isoflavan or isoflavene derivatives | BICBIO CO LTD (KR) | 2006-11-29 | — | — | CN | disclosed |
| CN-1259313-C | Process for preparation of azoxystrobin and analogues thereof | SYNGENTA LTD (GB) | 2006-06-14 | — | — | CN | disclosed |
| CN-1020901-C | METHOD FOR PREPARATION OF FUNGICIDES COMBINATION AND ITS USAGE | ICI PLC (GB) | 1993-05-26 | — | — | CN | disclosed |
| EP-0256667-B1 | SUBSTITUTED PHENYL-2-PROPENOIC ACID DERIVATIVES USEFUL IN AGRICULTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-30 | — | — | EP | disclosed |
| CN-1015543-B | FUNGICIDES | ICI LTD (GB) | 1992-02-19 | — | — | CN | disclosed |
| CN-1045777-A | Alpha-substitution-preparation method of 4-(quinoline-2-base-methoxyl group) toluylic acid and ester | BAYER AG (DE) | 1990-10-03 | — | — | CN | disclosed |
| CN-87105481-A | Mycocide and its production and use | — | 1988-03-30 | — | — | CN | disclosed |
| EP-0260794-A2 | Substituted phenyl-2-propenoic acid derivatives and their use as fungicides | ZENECA LIMITED (GB) | 1988-03-23 | — | — | EP | disclosed |
| CN-87105790-A | fungicide and preparation method thereof | — | 1988-03-23 | — | — | CN | disclosed |
| EP-0256667-A2 | Substituted phenyl-2-propenoic acid derivatives useful in agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-24 | — | — | EP | disclosed |
| CN-87103623-A | Fungicidal agents | ICI PLC (GB) | 1988-02-24 | — | — | CN | disclosed |
| US-4709078-A | Acrylates, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230073512-A1 | MODULATORS OF CULLIN 3 ADAPTOR KBTBD4 AS ANTI-CANCER COMPOUNDS | RBBP7, RBBP4, CUL4A | KMT2A 155/4885MEN1 3419/4885RECQL 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.