Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704744 | 0.86 | PRCP (0.41) | PRCPTLR2NAAACCR2GNAI3 | |
| SCHEMBL7707920 | 0.85 | KDM5A (0.35) | — | |
| SCHEMBL7704804 | 0.82 | PRCP (0.45) | PRCPTLR2NAAAGNAI3GNAO1 | |
| SCHEMBL7707500 | 0.75 | TLR2 (0.30) | TLR2 | |
| SCHEMBL7710604 | 0.75 | TLR2 (0.30) | TLR2 | |
| SCHEMBL7707925 | 0.72 | SIGMAR1 (0.42) | NAAA | |
| SCHEMBL7707952 | 0.72 | SIGMAR1 (0.42) | NAAA | |
| SCHEMBL9066004 | 0.71 | DNM1 (0.47) | TLR2 | |
| SCHEMBL7702119 | 0.71 | HTR2C (0.49) | — | |
| SCHEMBL9559762 | 0.67 | PRCP (0.54) | PRCPTLR2NAAACCR2GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263730-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | Applied Research Systems ARS Holding N.V. (AN) | 2002-12-11 | — | — | EP | claimed |
| WO-2001060798-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-08-23 | — | — | WO | claimed |