Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 4/20 | 0.33 |
| ▸ | NMT2 | O60551 | 3/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707952 | 1.00 | SIGMAR1 (0.42) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL7704744 | 0.85 | PRCP (0.41) | NAAA | |
| SCHEMBL7707920 | 0.85 | KDM5A (0.35) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL7704804 | 0.81 | PRCP (0.45) | KDM5APHF8KDM4CNAAA | |
| SCHEMBL7707500 | 0.74 | TLR2 (0.30) | — | |
| SCHEMBL7710604 | 0.74 | TLR2 (0.30) | — | |
| SCHEMBL7707901 | 0.73 | CTSC (0.44) | MC4RMC5RMC3R | |
| SCHEMBL7704806 | 0.73 | CTSC (0.44) | MC4RMC5RMC3R | |
| SCHEMBL7702120 | 0.73 | CTSC (0.44) | MC4RMC5RMC3R | |
| SCHEMBL7704766 | 0.72 | PRCP (0.38) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263730-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | Applied Research Systems ARS Holding N.V. (AN) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001060798-A1 | AMINE DERIVATIVES FOR THE TREATMENT OF APOPTOSIS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-08-23 | — | — | WO | disclosed |