Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136465 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL2567809 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL13174777 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL19645458 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL8620 | 1.00 | — | — | |
| SCHEMBL1164134 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL12338087 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL12513617 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL15492354 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 | |
| SCHEMBL16230018 | 1.00 | ALDH1A1 (1.00) | ALDH1A1EPHX1HIF1AAPLNRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713378-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2026-03-25 | — | — | EP | disclosed |
| US-20250388604-A1 | Compounds and Their Use as PDE4 Activators | MIRONID LIMITED (GB) | 2025-12-25 | — | — | US | disclosed |
| EP-4572762-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | Mironid Limited (GB) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024236000-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | COVESTRO DEUTSCHLAND AG (DE) | 2024-11-21 | — | — | WO | disclosed |
| EP-4464727-A1 | ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2024-11-20 | — | — | EP | disclosed |
| WO-2024038128-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | MIRONID LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2024-01-18 | — | — | US | disclosed |
| CN-114560838-B | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2023-09-15 | — | — | CN | disclosed |
| US-6638927-B2 | Melanocortin-4 receptor (MC4-R) agonists; treating obesity or diabetes; 4-((N-cyclohexyl-3,5-dimethyl-piperazine-1-carboximidoyl)-amino)-N-(2-(2,4 -dichlorophenyl) -ethyl)-benzamide for example | CHIRON CORPORATION | 2003-10-28 | — | — | US | disclosed |
| US-20030199499-A1 | Novel guanidinobenzamides | CHIRON CORPORATION | 2003-10-23 | — | — | US | disclosed |
| US-20020137939-A1 | Melanocortin-4 receptor (MC4-R) agonists; treating obesity or diabetes; 4-((N-cyclohexyl-3,5-dimethyl-piperazine-1-carboximidoyl)-amino)-N-(2-(2,4 -dichlorophenyl)-ethyl)-benzamide for example | CHIRON CORPORATION | 2002-09-26 | — | — | US | disclosed |
| WO-2002018327-A2 | GUANIDINOBENZAMIDES AS MC4-R AGONISTS | CHIRON CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
| US-5559273-A | POLYACRYLIC ACID, NONIONIC SURFACTANT | CIBA-GEIGY CORPORATION (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0574413-A1 | AQUEOUS TEXTILE AUXILIARY COMPOSITION. | CIBA GEIGY AG (CH) | 1993-12-22 | — | — | EP | disclosed |
| EP-0551219-A1 | Pyridylsulfonylurea, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992015664-A1 | AQUEOUS TEXTILE AUXILIARY COMPOSITION | CIBA-GEIGY AG (CH) | 1992-09-17 | — | — | WO | disclosed |
| EP-0000376-B1 | UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1980-08-20 | — | — | EP | disclosed |
| EP-0000376-A1 | Ureas and thioureas, processes for their preparation and their use as fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1979-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | ALDH1A1 4077/4885EPHX1 2485/4885HIF1A 3879/4885 |
| US-20030199499-A1 | Novel guanidinobenzamides | GUCY1B2, GPR119, GUCY1B1 | ALDH1A1 1371/4885EPHX1 3403/4885HIF1A 1825/4885 |
| US-20250388604-A1 | Compounds and Their Use as PDE4 Activators | PDE4A, PDE7A, PDE4B | ALDH1A1 989/4885EPHX1 1796/4885HIF1A 3471/4885 |
| US-20020137939-A1 | Melanocortin-4 receptor (MC4-R) agonists; treating obesity or diabetes; 4-((N-cyclohexyl-3,5-dimethyl-piperazine-1-carboximidoyl)-amino)-N-(2-(2,4 -dichlorophenyl)-ethyl)-benzamide for example | MC4R, MC5R, MC3R | ALDH1A1 2079/4885EPHX1 3470/4885HIF1A 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.