Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583858 | 0.84 | LTA4H (0.55) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL698135 | 0.81 | ALDH1A1 (0.47) | TSHRMAOAHTTSMN1; SMN2NPC1 | |
| SCHEMBL7700046 | 0.80 | GSTP1 (0.44) | GSTP1LTA4HTSHRERN1MCL1 | |
| SCHEMBL6406035 | 0.78 | LTA4H (0.75) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL2860844 | 0.78 | LTA4H (0.75) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL197414 | 0.78 | LTA4H (0.75) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL697263 | 0.78 | ABL1 (0.57) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24322042 | 0.77 | HTT (0.62) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL822790 | 0.77 | HTT (0.62) | GSTP1LTA4HTSHRNR1H2BAX | |
| SCHEMBL20419433 | 0.77 | HTT (0.62) | GSTP1LTA4HTSHRNR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |