Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710991 | 0.93 | CTSK (0.32) | CTSKCTSSCTSL | |
| SCHEMBL7708334 | 0.89 | ALDH1A1 (0.32) | CTSKCTSS | |
| Hydrochloric Acid SCHEMBL6992620 | 0.79 | ACE2 (0.32) | — | |
| SCHEMBL7713259 | 0.79 | USP2 (0.39) | — | |
| SCHEMBL7708245 | 0.78 | SMN1; SMN2 (0.31) | CTSKCTSS | |
| SCHEMBL7711367 | 0.78 | USP2 (0.38) | — | |
| SCHEMBL7711428 | 0.78 | PARP1 (0.39) | — | |
| SCHEMBL7089637 | 0.77 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8118427 | 0.75 | ESR1 (0.31) | — | |
| SCHEMBL7704894 | 0.75 | CTSK (0.31) | CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-1015437-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999012915-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |