SCHEMBL7704897

SCHEMBL7704897

CC(C)(O)C=CCC(C)(C)CCCCO

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704895 1.00 CYP4F2 (0.31) CYP4F2CYP4A11
SCHEMBL7701604 0.82
SCHEMBL6649205 0.82
SCHEMBL7591661 0.77 LMNA (0.38) CYP4F2CYP4A11
SCHEMBL7697580 0.77 FAAH (0.35)
SCHEMBL7697578 0.77 FAAH (0.35)
SCHEMBL6448246 0.72 SMN1; SMN2 (0.42) CYP4F2CYP4A11
SCHEMBL20438000 0.70 TDP1 (0.46) CYP4F2CYP4A11
SCHEMBL20438002 0.70 TDP1 (0.46) CYP4F2CYP4A11
SCHEMBL15297874 0.70 TDP1 (0.46) CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056716-B1 CYCLOHEXANEDIOLE DERIVATIVES BASILEA PHARMACEUTICA AG (CH) 2002-12-11 EP disclosed
US-6184422-B1 TREATMENT AND PREVENTION OF HYPERPROLIFERATIVE SKIN DISEASES; REVERSING CONDITIONS ASSOCIATED WITH PHOTODAMAGE; ANTITUMOR, -CARCINOGENIC AGENTS; PSORIASIS; DISORDERS OF NEOPLASTIC DISEASES; KERATINIZATION/KERATOSIS; ACNE; SEBORRHEA HOFFMAN-LA ROCHE INC. 2001-02-06 US disclosed