Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16577549 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL7776545 | 0.75 | METAP1 (0.37) | ALDH1A1HPGDALOX15TDP1RAB9A | |
| SCHEMBL30467249 | 0.75 | METAP1 (0.37) | ALDH1A1HPGDALOX15TDP1RAB9A | |
| SCHEMBL15746192 | 0.75 | ALDH1A1 (0.32) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL15746198 | 0.75 | ALDH1A1 (0.32) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL17193486 | 0.73 | CA12 (0.31) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL21694433 | 0.72 | ALDH1A1 (0.42) | TSHRALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL13799413 | 0.72 | DRD1 (0.40) | — | |
| SCHEMBL2973732 | 0.72 | ALDH1A1 (0.37) | ALDH1A1CA2ADRA2AADRA2BADRA2C | |
| SCHEMBL5953558 | 0.72 | DRD2 (0.38) | CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37573-E1 | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | BASELL POLYOLEFIN GMBH (DE) | 2002-03-05 | — | — | US | disclosed |
| US-5869584-A | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0582194-B1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | disclosed |
| EP-0582194-A1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-09 | — | — | EP | disclosed |