Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425386 | 0.85 | NR1I2 (0.38) | TSHR | |
| SCHEMBL5596819 | 0.84 | BTN3A1 (0.31) | — | |
| SCHEMBL6908926 | 0.80 | PTPN1 (0.39) | ACP3CTSGMEN1KMT2ACA2 | |
| SCHEMBL7705155 | 0.70 | CA2 (0.48) | CA2 | |
| SCHEMBL7127961 | 0.70 | SMN1; SMN2 (0.59) | TSHRMEN1KMT2A | |
| SCHEMBL309805 | 0.69 | TSHR (0.37) | TSHRMEN1KMT2ACA2 | |
| SCHEMBL4423326 | 0.67 | CA2 (0.48) | CA12CA2CA14 | |
| SCHEMBL4425076 | 0.67 | KDM4E (0.39) | MEN1KMT2A | |
| SCHEMBL8800480 | 0.66 | NCEH1 (0.35) | TSHR | |
| SCHEMBL9581623 | 0.66 | KEAP1 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194436-A1 | SULFONAMIDOMETHYL PHOSPHONATE INHIBITORS OF BETA-LACTAMASE | Methylgene, Inc. (CA) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001002411-A1 | SULFONAMIDOMETHYL PHOSPHONATE INHIBITORS OF β-LACTAMASE | METHYLGENE INC. (CA) | 2001-01-11 | — | — | WO | disclosed |