⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20433941 | 0.79 | HTT (0.46) | — | |
| SCHEMBL23846140 | 0.78 | CHRNB2 (0.41) | — | |
| SCHEMBL27859401 | 0.75 | HTT (0.46) | — | |
| SCHEMBL22951460 | 0.75 | LPO (0.41) | — | |
| SCHEMBL18250348 | 0.69 | TP53 (0.37) | — | |
| SCHEMBL25531776 | 0.69 | HTT (0.41) | — | |
| SCHEMBL308400 | 0.67 | LPO (0.55) | — | |
| SCHEMBL10770431 | 0.66 | TRPM8 (0.39) | — | |
| SCHEMBL21913153 | 0.66 | LPO (0.31) | — | |
| SCHEMBL14334531 | 0.66 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257828-A1 | SUBSTITUTED THIENOPYRIMIDINES THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2021-12-23 | — | — | WO | disclosed |
| EP-2960284-B1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-20170319517-A1 | METHODS, COMPOSITIONS, AND KITS FOR TREATING PAIN AND PRURITIS | THE GENERAL HOSPITAL CORPORATION | 2017-11-09 | — | — | US | disclosed |
| US-20160296592-A1 | Methods and Compositions for the Treatment of Proteinuric Diseases | THE GENERAL HOSPITAL CORPORATION | 2016-10-13 | — | — | US | disclosed |
| US-9345739-B2 | Methods and compositions for the treatment of proteinuric diseases | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-24 | — | — | US | disclosed |
| CN-102668232-B | Lithium-sulfur battery | SOLVAY FLUOR GMBH (DE) | 2016-05-04 | — | — | CN | disclosed |
| EP-2960284-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2015-12-30 | — | — | EP | disclosed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| CN-102574845-B | 1H-imidazo [4,5-c] qualone derivative | NOVARTIS AG (CH) | 2015-09-02 | — | — | CN | disclosed |
| CN-101512693-B | Electrolytic solution and electrolytic capacitor using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD | 2012-08-08 | — | — | CN | disclosed |
| US-20100297139-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION | 2010-11-25 | — | — | US | disclosed |
| CN-100490084-C | Polishing liquid for CMP process and polishing method | SANYO CHEMICAL IND LTD (JP) | 2009-05-20 | — | — | CN | disclosed |
| CN-1894818-A | Fuel for fuel cell, fuel cell and use thereof | KURITA WATER IND LTD (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1784770-A | Polishing liquid for CMP process and polishing method | SANYO CHEMICAL IND LTD (JP) | 2006-06-07 | — | — | CN | disclosed |
| US-6794385-B2 | ANTITUMOR AGENTS; ANTICANCER AGENTS; OSTEOPOROSIS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2004-09-21 | — | — | US | disclosed |