Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763199 | 0.77 | KDM1A (0.50) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL1763476 | 0.77 | KDM1A (0.50) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL4149119 | 0.75 | SCN9A (0.46) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL25973017 | 0.75 | SCN9A (0.46) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL13811323 | 0.75 | KDM1A (0.52) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL27999354 | 0.75 | KDM1A (0.52) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL9634176 | 0.74 | KDM1A (0.43) | KDM1ASLC6A4SLC6A2SLC6A3MTNR1A | |
| SCHEMBL10800761 | 0.73 | MTNR1A (0.50) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL2710242 | 0.70 | HTR2C (0.56) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL30368566 | 0.70 | HTR2C (0.56) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002088133-A1 | ANTIPSYCHOTIC AMINOMETHYL DERIVATIVES OF 7,8-DIHYDRO-3H-6,9-DIOXA-2,3-DIAZA-CYCLOPENTA[a]NAPHTHALENE | WYETH (US) | 2002-11-07 | — | — | WO | disclosed |