Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.65 |
| ▸ | SHBG | P04278 | 4/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12615684 | 0.90 | SERPINA6 (0.64) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL1725885 | 0.89 | SERPINA6 (0.60) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL15530357 | 0.87 | SERPINA6 (0.60) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL3500490 | 0.87 | SERPINA6 (0.60) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL3816344 | 0.87 | SERPINA6 (0.72) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL517355 | 0.85 | SHBG (0.69) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL16188696 | 0.85 | SHBG (0.69) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL16188590 | 0.85 | SHBG (0.69) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL7615553 | 0.85 | SHBG (0.69) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL16741266 | 0.85 | SHBG (0.69) | SERPINA6SHBGSLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212345-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | Akzo Nobel N.V. (NL) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000059920-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | AKZO NOBEL N.V. (NL) | 2000-10-12 | — | — | WO | disclosed |