SCHEMBL7705491

SCHEMBL7705491

Cc1cc(C(=O)Cl)c(Cl)cc1C(=O)Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MYC P01106 1/20 0.34
NR4A1 P22736 1/20 0.34
NNMT P40261 1/20 0.34
RAB9A P51151 4/20 0.33
NPC1 O15118 3/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK13 O15264 2/20 0.33
MAPK12 P53778 2/20 0.33
MAPK11 Q15759 2/20 0.33
MAPK14 Q16539 2/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10630827 0.88 SMN1; SMN2 (0.35) SMN1; SMN2TSHRCASP1MAPTKDM4E
SCHEMBL2154184 0.88 ALDH1A1 (0.37) SMN1; SMN2MAPTKDM4ENNMTALDH1A1
SCHEMBL10630611 0.86 CD44 (0.39) SMN1; SMN2TSHRCASP1MAPTKDM4E
SCHEMBL8465356 0.86 CD44 (0.39) SMN1; SMN2TSHRCASP1MAPTKDM4E
SCHEMBL101268 0.85 TSHR (0.42) SMN1; SMN2TSHRCASP1MAPTKDM4E
SCHEMBL1313097 0.83 BCHE (0.39) SMN1; SMN2MAPTKDM4ERAB9AALDH1A1
SCHEMBL25304375 0.81 ALDH1A1 (0.33) SMN1; SMN2TSHRCASP1MAPTKDM4E
SCHEMBL15385122 0.81 POLB (0.43) SMN1; SMN2TSHRMAPTRAB9ANPC1
SCHEMBL1312984 0.80 TSHR (0.39) SMN1; SMN2TSHRCASP1MAPTKDM4E
SCHEMBL11670395 0.80 SMN1; SMN2 (0.37) SMN1; SMN2MAPTKDM4ENNMTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6346310-B1 MAGNETIC LAYER ON FLEXIBLE SUPPORT AND BACKCOAT LAYER ON SURFACE FUJI PHOTO FILM CO., LTD. (JP) 2002-02-12 US disclosed
EP-1049076-A1 MAGNETIC RECORDING MEDIUM FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed