SCHEMBL101268

SCHEMBL101268

O=C(Cl)c1cc(Cl)c(C(=O)Cl)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
CASP1 P29466 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 7/20 0.42
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
SLC9A1 P19634 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
TP53 P04637 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
AKR1C4 P17516 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312984 0.94 TSHR (0.39) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL9812995 0.91 TSHR (0.41) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL7656107 0.88 ALDH1A1 (0.42) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL7929417 0.85 ALDH1A1 (0.45) TSHRSMN1; SMN2ALDH1A1MAPTSLC9A1
SCHEMBL7705491 0.85 SMN1; SMN2 (0.34) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL8465356 0.85 CD44 (0.39) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL3820327 0.82 POLB (0.53) TSHRSMN1; SMN2ALDH1A1MAPTALOX15
SCHEMBL29098888 0.82 GAA (0.43) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL10630827 0.82 SMN1; SMN2 (0.35) TSHRCASP1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL1180396 0.80 ALDH1A1 (0.45) TSHRSMN1; SMN2ALDH1A1MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113174037-A Linear high heat-resistant oxidized polyaryletherketone ketone and preparation method thereof 江阴市博生新材料科技有限公司 2021-07-27 CN claimed
CN-1057137-C Para-aramide dope of low degree of polymerization, para-aramide fiber and para-aramide pulp produced therefrom and processes for producing the same SUMITOMO CHEMICAL CO (JP) 2000-10-04 CN claimed
EP-0572002-B1 Para-aramide dope of low degree of polymerization, para-aramide fiber and para-aramide pulp produced therefrom and processes for producing the same SUMITOMO CHEMICAL CO (JP) 2000-08-30 EP claimed
CN-1082634-A Low polymerization degree is right-the polyarylamide spinning solution SUMITOMO CHEMICAL CO (JP) 1994-02-23 CN claimed
EP-0572002-A2 Para-aramide dope of low degree of polymerization, para-aramide fiber and para-aramide pulp produced therefrom and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-12-01 EP claimed
US-4395534-A Process for producing aromatic polyester carbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-07-26 US claimed
JP-60016952-A None JP disclosed
US-12577369-B2 High tenacity filled films comprising a polymer having imidazole groups DUPONT SAFETY & CONSTRUCTION, INC. (US) 2026-03-17 US disclosed
EP-4590736-A1 HIGH DIELECTRIC CONSTANT NEAT POLYMERIC FILM DuPont Safety & Construction, Inc. (US) 2025-07-30 EP disclosed
EP-4590740-A1 HIGH TENACITY FILLED FILMS COMPRISING A POLYMER HAVING IMIDAZOLE GROUPS DuPont Safety & Construction, Inc. (US) 2025-07-30 EP disclosed
CN-120202242-A High dielectric constant pure polymer film 杜邦安全与建筑公司 2025-06-24 CN disclosed
EP-4130371-B1 STITCHED REINFORCING-FIBER BASE MATERIAL, PREFORM MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, AND PRODUCTION METHOD FOR STITCHED REINFORCING-FIBER BASE MATERIAL, PREFORM MATERIAL, AND FIBER-REINFORCED COMPOSITE MATERIAL TEIJIN LTD (JP) 2024-07-31 EP disclosed
EP-2802694-B1 METHOD FOR REMOVING SULFUR FROM FIBER USING A WEAK BASE DUPONT SAFETY & CONSTRUCTION INC (US) 2024-05-08 EP disclosed
US-4339601-A DECARBOXYLATION, DIMETHYL SULFOXIDE, DIMETHYLFORMAMIDE UNION CARBIDE CORPORATION (US) 1982-07-13 US disclosed
US-4252979-A 2,5-DICHLORO-3-NITRO, HERBICIDES AMCHEM PRODUCTS INC. (US) 1981-02-24 US disclosed
US-RE30352-E AMIDE OR UREA CONTAINING SALT, SULFURIC ACID, HYDROFLUORIC ACID, OR HALO- OR METHANESULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed
US-4214071-A Amide-imide polymers WESTINGHOUSE ELECTRIC CORP. (US) 1980-07-22 US disclosed
US-4172938-A Process for producing polyamides with lactam or urea solvent and CaCl2 TEIJIN LIMITED (JP) 1979-10-30 US disclosed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577369-B2 High tenacity filled films comprising a polymer having imidazole groups DDT, DDC, PNMT TSHR 4624/4885CASP1 2461/4885SMN1; SMN2 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.