Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14737029 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7709625 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7716014 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL7709653 | 0.82 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDGAAPTGDR2 | |
| SCHEMBL14736987 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL2592881 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7712484 | 0.80 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL7714650 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7713154 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL14737662 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDGAAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |