Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713141 | 0.90 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL2593093 | 0.88 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7717394 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7712445 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7715665 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL2583988 | 0.83 | KDM4E (0.42) | ALDH1A1KDM4EHPGDS1PR1BRAF | |
| SCHEMBL7705939 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL7714336 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL2591370 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDGAAS1PR1 | |
| SCHEMBL14737129 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDGAAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |