Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14737621 | 0.91 | PKM (0.41) | ALDH1A1GAAPTGDR2KDM4EHPGD | |
| SCHEMBL7709625 | 0.85 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL7705939 | 0.82 | ALDH1A1 (0.40) | ALDH1A1GAAPTGDR2KDM4EHPGD | |
| SCHEMBL14736856 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAATMKDM4EHPGD | |
| SCHEMBL7716014 | 0.80 | ALDH1A1 (0.36) | ALDH1A1GAAKDM4EHPGDLMNA | |
| SCHEMBL7714338 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAATSHRKDM4EHPGD | |
| SCHEMBL14737591 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAATSHRKDM4EHPGD | |
| SCHEMBL2585450 | 0.76 | ALDH1A1 (0.42) | ALDH1A1GAAATMTSHRKDM4E | |
| SCHEMBL7712484 | 0.75 | ALDH1A1 (0.33) | ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL14737564 | 0.74 | ALDH1A1 (0.42) | ALDH1A1GAAKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |