Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | FABP2 | P12104 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699061 | 0.85 | GSTP1 (0.45) | PTGS2TSHRHSP90AA1 | |
| SCHEMBL5710969 | 0.79 | CA1 (0.39) | PTGS1HPGDTSHRHTR2CLMNA | |
| SCHEMBL28926448 | 0.79 | BACE1 (0.39) | CDC25ACDC25BPTGS1MEN1PTGS2 | |
| SCHEMBL28926455 | 0.78 | PTPRC (0.38) | PTGS1MEN1PTGS2KMT2AHPGD | |
| SCHEMBL6679695 | 0.75 | AKR1C3 (0.39) | HPGDTSHRADRA2BAKR1C3AKR1C2 | |
| SCHEMBL28926405 | 0.75 | PTPRC (0.43) | MEN1KMT2AHPGDAKR1C3AKR1C2 | |
| SCHEMBL2160199 | 0.72 | CDC25A (0.38) | CDC25ACDC25BMEN1PTGS2KMT2A | |
| SCHEMBL18419898 | 0.72 | GABRA1 (0.33) | PTGS1HPGDTSHRHTR2CLMNA | |
| SCHEMBL10670019 | 0.71 | CKS1B (0.38) | MEN1KMT2AHPGDLMNAMAPT | |
| SCHEMBL6262323 | 0.70 | LMNA (0.31) | PTGS1HPGDTSHRHTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |