SCHEMBL7706646

SCHEMBL7706646

O=[C]c1ccc(F)c(F)c1[C]=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994176 0.82 CES2 (0.37) CES2CES1
SCHEMBL2052718 0.80 CES2 (0.41) CES2CES1
SCHEMBL9022619 0.76
SCHEMBL7703149 0.73 CES2 (0.31) CES2CES1
SCHEMBL7705802 0.71 CES2 (0.36) CES2CES1
SCHEMBL4791076 0.70 CES2 (0.33) CES2CES1
SCHEMBL10535180 0.69
SCHEMBL3974422 0.69 CA1 (0.39) CES2CES1
SCHEMBL357469 0.68 CES2 (0.43) CES2CES1
SCHEMBL11020603 0.68 TRPA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6355615-B1 CYCLIC POLYAMIDEESTER COPOLYMERS BAYER AKTIENGESELLSCHAFT (DE) 2002-03-12 US claimed
EP-0986549-A1 DESOXYCYCLODEPSIPEPTIDES AND THEIR USE FOR COMBATTING ENDOPARASITES Bayer Aktiengesellschaft (DE) 2000-03-22 EP claimed
WO-1998055469-A1 DESOXYCYCLODEPSIPEPTIDES AND THEIR USE FOR COMBATTING ENDOPARASITES BAYER AKTIENGESELLSCHAFT (DE) 1998-12-10 WO claimed
US-6355615-B1 CYCLIC POLYAMIDEESTER COPOLYMERS BAYER AKTIENGESELLSCHAFT (DE) 2002-03-12 US disclosed
EP-0986549-A1 DESOXYCYCLODEPSIPEPTIDES AND THEIR USE FOR COMBATTING ENDOPARASITES Bayer Aktiengesellschaft (DE) 2000-03-22 EP disclosed
WO-1998055469-A1 DESOXYCYCLODEPSIPEPTIDES AND THEIR USE FOR COMBATTING ENDOPARASITES BAYER AKTIENGESELLSCHAFT (DE) 1998-12-10 WO disclosed
EP-0055630-A2 Method for the preparation of fluorophthalamic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1982-07-07 EP disclosed