SCHEMBL3974422

SCHEMBL3974422

O=[C]c1c(F)c(F)cc(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA4 P22748 2/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3716069 0.83 CA12 (0.32) CA1CA2CA12CA7CA13
SCHEMBL8119705 0.78 CA1 (0.32) CA1CA2CA4CA12CA7
SCHEMBL9116623 0.77
SCHEMBL8994176 0.74 CES2 (0.37) CES2CES1
SCHEMBL10701289 0.74 MAPK1 (0.33)
SCHEMBL317183 0.74
SCHEMBL8116820 0.72 HDAC1 (0.32)
SCHEMBL9712405 0.72 TRPA1 (0.34)
SCHEMBL3245816 0.71 HPRT1 (0.37) CA1CA2
SCHEMBL21931937 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877461-B1 MODIFICATION OF THERMOPLASTIC POLYMERS MEDTRONIC INC (US) 2009-05-06 EP claimed
EP-1877461-A2 MODIFICATION OF THERMOPLASTIC POLYMERS Medtronic, Inc. (US) 2008-01-16 EP claimed
US-20060223955-A1 Modification of thermoplastic polymers MEDTRONIC, INC. 2006-10-05 US claimed
WO-2006102603-A2 MODIFICATION OF THERMOPLASTIC POLYMERS MEDTRONIC, INC. (US) 2006-09-28 WO claimed
EP-0730592-A1 DERIVATIVES OF 2,3,5,6-TETRAFLUOROBENZOIC ACID AND THEIR USE IN COMBATING PESTS BAYER AG (DE) 1996-09-11 EP claimed
EP-0725787-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-08-14 EP claimed
WO-1996006853-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-03-07 WO claimed
WO-1995014688-A1 DERIVATIVES OF 2,3,5,6-TETRAFLUOROBENZOIC ACID AND THEIR USE IN COMBATING PESTS BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO claimed
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed
EP-4164891-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-04-19 EP disclosed
CN-115768631-A Fluorescent composition comprising at least one benzoxazole compound for protecting products 犯罪科学技术公司 2023-03-07 CN disclosed
WO-2021250358-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2021-12-16 WO disclosed
US-7538163-B2 Modification of thermoplastic polymers MEDTRONIC, INC. (US) 2009-05-26 US disclosed
EP-1877461-B1 MODIFICATION OF THERMOPLASTIC POLYMERS MEDTRONIC INC (US) 2009-05-06 EP disclosed
WO-2006102603-A2 MODIFICATION OF THERMOPLASTIC POLYMERS MEDTRONIC, INC. (US) 2006-09-28 WO disclosed
CN-1205468-C Method and reagents for quantification of solid-phase reactions using fluorine NMR AVENTISS PHARMACEUTICAL PRODUC (US) 2005-06-08 CN disclosed
WO-1997040007-A1 2,3,5,6-TETRAFLUOROBENZOIC ACID AMIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-30 WO disclosed
US-5574146-A Oligonucleotide synthesis with substituted aryl carboxylic acids as activators BECKMAN INSTRUMENTS, INC. (US) 1996-11-12 US disclosed
EP-0725787-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-08-14 EP disclosed
WO-1996006853-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 CA1 4746/4885CA2 4663/4885CA4 3785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.