Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711047 | 0.91 | MRGPRX4 (0.43) | ALDH1A1GAAKDM4EHPGDMRGPRX4 | |
| SCHEMBL14737152 | 0.89 | ALDH1A1 (0.48) | PARP10ALDH1A1KDM4EHPGDPARP1 | |
| SCHEMBL7717628 | 0.85 | KCNJ1 (0.38) | PARP10ALDH1A1KDM4EPARP1ATM | |
| SCHEMBL7706819 | 0.84 | KDM4E (0.37) | ALDH1A1GAAKDM4EHPGDMAOB | |
| SCHEMBL2593760 | 0.84 | KDM4E (0.38) | PARP10ALDH1A1KDM4EHPGDPARP1 | |
| SCHEMBL2592764 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMRGPRX4 | |
| SCHEMBL2591335 | 0.78 | KDM4E (0.46) | ALDH1A1GAAKDM4EHPGDATM | |
| SCHEMBL2591657 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDATMMRGPRX4 | |
| SCHEMBL7717394 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4EHPGDMRGPRX4 | |
| SCHEMBL7713141 | 0.76 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |