Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 10/20 | 0.36 |
| ▸ | CA1 | P00915 | 8/20 | 0.36 |
| ▸ | CA12 | O43570 | 8/20 | 0.36 |
| ▸ | CA7 | P43166 | 7/20 | 0.36 |
| ▸ | CA9 | Q16790 | 7/20 | 0.36 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | CA5A | P35218 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591462 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1HPGDCA2CA1 | |
| SCHEMBL2584463 | 0.87 | KDM4E (0.48) | KDM4EALDH1A1HPGDCA2CA1 | |
| SCHEMBL7706649 | 0.84 | PARP10 (0.38) | KDM4EALDH1A1HPGDMAOBGAA | |
| SCHEMBL2581967 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1HPGDCA2CA1 | |
| SCHEMBL2584646 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDCA2CA1 | |
| SCHEMBL2583872 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HPGDALOX5APFEN1 | |
| SCHEMBL2594850 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDALOX5APFEN1 | |
| SCHEMBL7711047 | 0.80 | MRGPRX4 (0.43) | KDM4EALDH1A1HPGDALOX5APFEN1 | |
| SCHEMBL2592309 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDALOX5APFEN1 | |
| SCHEMBL17599643 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HPGDCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011134468-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-11-03 | — | — | WO | disclosed |