Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24277478 | 0.86 | SPR (0.74) | SPRHDAC8TRPV1PTGS2FAAH | |
| SCHEMBL6399249 | 0.86 | SPR (0.74) | SPRHDAC8TRPV1PTGS2FAAH | |
| SCHEMBL20168578 | 0.86 | HDAC8 (0.77) | SPRHDAC8TRPV1PTGS2FAAH | |
| SCHEMBL29804259 | 0.86 | HDAC8 (0.77) | SPRHDAC8TRPV1PTGS2FAAH | |
| SCHEMBL20168582 | 0.86 | HDAC8 (0.77) | SPRHDAC8TRPV1PTGS2FAAH | |
| SCHEMBL1132347 | 0.85 | CTSC (0.72) | HDAC8FAAHKDM4EALDH1A1CYP3A4 | |
| SCHEMBL18381197 | 0.85 | CTSC (0.72) | HDAC8FAAHKDM4EALDH1A1CYP3A4 | |
| SCHEMBL1132363 | 0.85 | CTSC (0.72) | HDAC8FAAHKDM4EALDH1A1CYP3A4 | |
| SCHEMBL1132343 | 0.85 | CTSC (0.76) | SPRHDAC8TRPV1PTGS2FAAH | |
| SCHEMBL2824991 | 0.85 | TRPV1 (0.64) | SPRHDAC8TRPV1PTGS2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6368788-B1 | IMMUNOSUPPRESSANTS FOR HTLV AND VIRICIDES | CYTRAN, INC. | 2002-04-09 | — | — | US | disclosed |
| US-5811399-A | Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants | CYTRAN, INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5807830-A | ADMINISTERING GLUTAMIC ACID, TRYPTOPHAN DIPEPTIDE | CYTOVEN J.V. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5770576-A | ADMINISTERING GLUTAMIC ACID-TRYPTOPHAN DIPEPTIDE TO STIMULATE BINDING FUNCTION OF T-LYMPHOCYTES | CYTRAN, INC. (US) | 1998-06-23 | — | — | US | disclosed |