Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706764 | 0.81 | THRB (0.56) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL12545749 | 0.81 | RECQL (0.65) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL2170056 | 0.78 | ALDH1A1 (0.64) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL14845420 | 0.78 | THRB (0.53) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL12545717 | 0.78 | RAB9A (0.55) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL31544600 | 0.77 | RECQL (0.69) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL6319718 | 0.76 | ALDH1A1 (0.66) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL28487128 | 0.75 | ALDH1A1 (0.55) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL31519040 | 0.74 | RAB9A (0.56) | THRBRECQLALDH1A1RAB9ANPC1 | |
| SCHEMBL8031188 | 0.74 | RAB9A (0.65) | THRBRECQLALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362138-B1 | WEAR AND OXIDATION RESISTANCE; FOR INTERNAL COMBUSTION ENGINES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-26 | — | — | US | disclosed |
| US-6150307-A | Heterocyclic thioethers as additives for lubricants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-11-21 | — | — | US | disclosed |